Many translated example sentences containing “displasia fibrosa” – English- Spanish dictionary and search engine for English translations. presentamos un caso de displasia fibrosa monostótica localizada en el seno frontal fronto-orbitaria. la displasia fibrosa es una alteración ósea infrecuente con. RESUMEN: La displasia ósea florida (DOF) es una patología benigna del maxilar y mandíbula en la que se sustituye la arquitectura normal del hueso por un.

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Fibrous dysplasia FD is a non-neoplastic tumor-like congenital process, manifested as a localised defect in osteoblastic differentiation and maturation, with the replacement of normal bone with large fibrous stroma and islands of immature woven bone.

Pathology Outlines – Fibrous dysplasia

Fibrous dysplasia dispalsia a varied radiographic appearance. If asymptomatic, it does not require treatment. The remainder of this article concerns itself with skeletal fibrous dysplasia.

For a discussion of craniofacial fibrous dysplasia and cherubismplease refer to the respective articles. In polyostotic form, patients usually present by 10 years old.


There is no recognised gender predilection 9. The condition is often an incidental finding and is usually painless. Alternatively, it may present due to bony expansion or remodelling. Morbidity may arise from compression and displacement of adjacent structures.

This is particularly true in craniofacial fibrous dysplasia, osae the content of the orbit or cranial nerves may be compressed. Fibrous dysplasia is due to developmental dysplasia and focal arrest in normal osteoblastic activity secondary to a non-hereditary mutation which results in the presence of all of the components of normal bone with a lack of normal differentiation into their mature structures. Macroscopically, lesions are intramedullary and well circumscribed with abnormal whitish-grey color.


Microscopically it manifests as large fibrous matrix with scattered curvilinear irregularly shaped trabeculae of immature, inadequately mineralized bone 6. Dosplasia is no rimming by osteoblasts differentiating feature from cemento-ossifying fibroma. It is usually asymptomatic ffibrosa 2 nd -3 rd decade but can be seen throughout adulthood 6.

After puberty, the disease becomes inactive, and monostotic form does not progress to polyostotic form. As expected dsplasia presents earlier, typically in childhood mean age of 8 years with two-thirds symptomatic by the age of Ribs are the most common site of monostotic fibrous dysplasia.

Fibrous dysplasia is the most common cause of a benign expansile lesion of a rib see rib lesions. MRI is not particularly useful in differentiating fibrous dysplasia from other entities as there is marked variability in the appearance of the bone lesions, and they can often resemble a tumor or more aggressive lesions. Demonstrates increased tracer dosplasia on Tc 99 bone scans lesions remain metabolically active into adulthood.

Usually, no treatment is required as the bone lesions usually do not progress beyond puberty. If a mass effect is severe, then surgical decompression may be considered. The monostotic form does not transform or progress oaea the polyostotic form Not surprisingly, bone affected by fibrous dysplasia is weaker displxsia normal and thus susceptible to pathological fractures.

It should be noted that many reported cases may psea to previous treatment with displaska therapy 6. Due to the variability of the appearance of fibrous dysplasia the potential differential is very long but will be significantly influenced by the dominant pattern. To quiz yourself on this article, log in to see multiple choice questions. The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.


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Articles Cases Courses Quiz. About Blog Go ad-free. Cases and figures Imaging differential diagnosis. Read it at Google Books – Find it at Amazon. Related Radiopaedia articles Bone tumours The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the pediatric patient. Edit article Share article View revision history.

Synonyms or Alternate Spellings: Support Radiopaedia and see fewer ads. Case 1 Case 1. Case 2 Case 2. Case 6 Case 6. Case 7 Case 7. Case 8 Case 8. Case 9 Case 9.

Case 10 Case Case 12 Case Case 13 Case Case 14 Case Case 15 Case Case 16 Case Case 17 Case Case 28 Case Mazabraud syndrome with Fibrksa Case Mazabraud syndrome with ABC. Case 31 Case Case 32 Case Paget’s disease Paget’s disease. Unicameral bone cyst Unicameral bone cyst. Loading Stack – 0 images remaining.