Request PDF on ResearchGate | Intérêt des acides biliaires dans la cholestase gravidique | Intrahepatic cholestasis during pregnancy is a risk factor for. La cholestase gravidique a été reliée à des critères de jugement maternels et fœtaux/néonatals indésirables. Du fait que la physiopathologie est mal comprise, . Interventions pour le traitement de la cholestase gravidique. This is not the most recent version of this Review. view the current version 24 June

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Bile acids, Ursodeoxycholic acid, Prematurity, Pruritus. Journal page Archives Contents list. Top of the page – Article Outline. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen.

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Treatment by the bile acid ursodeoxycholic acid ccholestase pruritus and decreases the frequency of fetal complications, without side effects in the mother or baby.

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Cholestasis of pregnancy presents with pruritus, sometimes incapacitating, less frequently by jaundice. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Clinical signs and biochemical abnormalities normalize rapidly after dholestase, at most after 3 to 4 weeks.

Its prevalence in France is of the order of 1 per pregnancies.


Contact Help Who are we? Gravity of the disease comes from the occurrence of fetal complications, in particular prematurity often induced by obstetrical teams and its pulmonary complications, and sudden intra-uterine fetal death.

In forms with severe pruritus, early delivery by induced labor gavidique 37 and 38 weeks may be necessary. It occurs during the second or third choleshase. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data.


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Hépato-Gastro & Oncologie Digestive

La cholestase gravidique Intrahepatic cholestasis of pregnancy. Outline Masquer le plan. The susceptibility is explained by polymorphisms of genes encoding hepatocytic transport proteins that are important for bile secretion.

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Liver choolestase are abnormal, with mainly an increase in serum transaminases and bile acids. The disease is probably due to susceptibility to estrogens and progesterone, whose serum concentration is elevated during pregnancy and which are cholestatic. Besides disturbing pruritus, maternal prognosis is good.

It is slightly more frequent during twin pregnancies.